Cardiovascular and gastrointestinal risks of nonsteroidal antiinflammatory drugs revisited: Comment on the article by the American College of rheumatology Ad Hoc group on use of selective and nonselective nonsteroidal antiinflammatory drugs
نویسندگان
چکیده
منابع مشابه
Use of Nonsteroidal Antiinflammatory Drugs
Clinical trial data have prompted questions about the degree to which patients and their physicians should consider an increased risk of cardiovascular or cerebrovascular events when selecting medications for pain relief. Since the 2005 publication of a Science Advisory on the use of nonsteroidal antiinflammatory drugs (NSAIDs) by the American Heart Association,1 several important events have o...
متن کاملLetter by Kurth regarding article, "Nonsteroidal antiinflammatory drugs, acetaminophen, and the risk of cardiovascular events".
BACKGROUND Although randomized trials of cyclooxygenase-2 (COX-2) inhibitors have shown increased cardiovascular risk, studies of nonselective, nonsteroidal antiinflammatory drugs (NSAIDs) and acetaminophen have been inconsistent. METHODS AND RESULTS We examined the influence of NSAIDs and acetaminophen on the risk of major cardiovascular events (nonfatal myocardial infarction, fatal coronary...
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Results of 3 previous studies suggest that use of aspirin is related to a reduced risk of endometrial cancer, at least in obese women (body mass index, > or =30 kg/m(2)). Using data obtained in a population-based, case-control study in western Washington State, the authors examined this question. Between 2003 and 2005, 410 women diagnosed with invasive endometrial cancer and 356 controls were i...
متن کاملCataract surgery and nonsteroidal antiinflammatory drugs.
Nonsteroidal antiinflammatory drugs (NSAIDs) have become an important adjunctive tool for surgeons performing routine and complicated cataract surgery. These medications have been found to reduce pain, prevent intraoperative miosis, modulate postoperative inflammation, and reduce the incidence of cystoid macular edema (CME). Whether used alone, synergistically with steroids, or for specific hig...
متن کاملColonic side effects of nonsteroidal antiinflammatory drugs.
Non-steroidal anti-inflammatory drugs (NSAIDs) are a widely prescribed group of drugs, known to be responsible for many cases of gastroduodenal ulcers by inhibiting cyclo-oxygenase (1). The incidence of side effects while taking NSAID therapy is high, and has been reported to approach 70% in patients receiving long-term therapy. The most frequent complications are those involving the gastroduod...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 2009
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.24159